Does Newer Mean Better?

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Good to keep in mind the risk/benefit ratios.

invasivecardiology

Neil Ruparelia, DPhil, MRCP1,2;  Azeem Latib, MD1; and Antonio Colombo, MD1

1San Raffaele Scientific Institute, Milan, Italy
2Imperial College, London, United Kingdom

Transcatheter aortic valve implantation (TAVI) has rapidly expanded following the first reported case in 2002 to now being the recommended treatment option for high-risk or inoperable patients with severe symptomatic aortic stenosis (AS). While the first studies clearly demonstrated safety and efficacy of this revolutionary technology, they also identified some limitations including vascular complications, stroke, the requirement for permanent pacemaker implantation, and residual aortic regurgitation. Subsequent studies have consistently demonstrated that the presence of more-than-mild paravalvular regurgitation and the occurrence of a vascular complication to be independent predictors of mortality. In an attempt to reduce the incidence of these limitations, a number of technological refinements have been made to TAVI devices and their delivery systems. We therefore aimed to investigate the impact of these changes relating to intraprocedural…

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